SCHEMBL13864981

SCHEMBL13864981

COC(=O)c1cccc(C(=O)Oc2ccc(C(c3ccccc3)(c3ccccc3)c3ccc(C)cc3)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.56
▸ TDP1 Q9NUW8 3/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ RAB9A P51151 1/20 0.47
▸ KMT2A Q03164 5/20 0.46
▸ TSHR P16473 1/20 0.45
▸ TCF4 P15884 1/20 0.44
▸ CTNNB1 P35222 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.43
▸ THRB P10828 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ FNTA P49354 1/20 0.42
▸ FNTB P49356 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13864963 0.91 MAPT (0.55) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL13864928 0.91 MAPT (0.60) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL13865046 0.87 MAPT (0.56) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL13864989 0.87 MAPT (0.51) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL13161726 0.84 MAPT (0.66) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL12023305 0.84 MAPT (0.56) MAPTTDP1RAB9AKMT2ATCF4
SCHEMBL13865016 0.84 KMT2A (0.45) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL19343631 0.82 TDP1 (0.46) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL10630065 0.82 TSHR (0.62) MAPTTDP1L3MBTL1RAB9AKMT2A
SCHEMBL7212880 0.82 KMT2A (0.63) MAPTTDP1L3MBTL1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090123854-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-14 — — US disclosed
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