SCHEMBL13865047

SCHEMBL13865047

COC(=O)c1ccc(-c2ccc(C(=O)Oc3c(C)cc(C(c4ccccc4)(c4ccccc4)c4cc(C)c(C)c(C)c4)cc3C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.47
▸ PTPN1 P18031 1/20 0.45
▸ TSHR P16473 1/20 0.44
▸ PPARA Q07869 1/20 0.41
▸ L3MBTL1 Q9Y468 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ MAPT P10636 5/20 0.40
▸ RAB9A P51151 4/20 0.40
▸ PDCD1 Q15116 1/20 0.40
▸ CD274 Q9NZQ7 1/20 0.40
▸ CASP3 P42574 1/20 0.40
▸ SENP8 Q96LD8 1/20 0.40
▸ SENP7 Q9BQF6 1/20 0.40
▸ SENP6 Q9GZR1 1/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ SGK1 O00141 1/20 0.39
▸ CAMKK2 Q96RR4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13864905 0.96 TSHR (0.47) EGFRPTPN1TSHRPPARAL3MBTL1
SCHEMBL13865025 0.89 EGFR (0.46) EGFRPTPN1TSHRPPARAL3MBTL1
SCHEMBL13864987 0.89 TSHR (0.45) TSHRPPARAL3MBTL1POLBKMT2A
SCHEMBL13864904 0.85 TSHR (0.46) EGFRTSHRPPARAL3MBTL1SMN1; SMN2
SCHEMBL13865022 0.84 TDP1 (0.44) EGFRPTPN1SMN1; SMN2MEN1KMT2A
SCHEMBL17756693 0.81 TDP1 (0.52) TSHRPPARASMN1; SMN2MEN1KMT2A
SCHEMBL13864911 0.80 TDP1 (0.47) TSHRMEN1KMT2AMAPTRAB9A
SCHEMBL13865048 0.80 PTPN1 (0.45) EGFRPTPN1TSHRSMN1; SMN2MEN1
SCHEMBL13865029 0.79 CA12 (0.49) EGFRPTPN1L3MBTL1SMN1; SMN2MEN1
SCHEMBL13865046 0.79 MAPT (0.56) EGFRPTPN1TSHRL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090123854-A1 IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-14 — — US disclosed
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