Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865117 | 0.89 | MAPT (0.52) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL13772497 | 0.78 | MEN1 (0.54) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL4124643 | 0.75 | POLB (0.53) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL13865134 | 0.75 | KMT2A (0.51) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL4124642 | 0.75 | POLB (0.53) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL4127562 | 0.75 | POLB (0.53) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL4127567 | 0.75 | POLB (0.53) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL2394131 | 0.74 | ACACB (0.50) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL5016632 | 0.73 | TSHR (0.73) | MEN1KMT2APOLBLMNAMAPT | |
| SCHEMBL6398811 | 0.73 | MAPT (0.69) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057133-A2 | A PROCESS FOR THE SYNTHESIS OF 2-[2-[4-[(4-CHLOROPHENYL)PHENYL METHYL]-1-PIPERAZINYL] ETHOXY ACETIC ACID | GLENMARK GENERICS LIMITED (IN) | 2009-05-07 | — | — | WO | disclosed |