Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386516 | 1.00 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1382951 | 1.00 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1381707 | 0.94 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4523242 | 0.94 | KCNH2 (0.37) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4507787 | 0.93 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1384149 | 0.93 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7555874 | 0.92 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7555884 | 0.92 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4523536 | 0.92 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4502095 | 0.92 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | claimed |