Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313133 | 0.92 | PDE4B (0.72) | PDE4B | |
| SCHEMBL2774131 | 0.91 | PDE4B (0.71) | PDE4B | |
| SCHEMBL2772023 | 0.91 | PDE4B (0.71) | PDE4B | |
| SCHEMBL2774528 | 0.90 | PDE4B (0.76) | PDE4B | |
| SCHEMBL2775249 | 0.89 | PDE4B (0.69) | PDE4B | |
| SCHEMBL6848346 | 0.89 | PDE4B (0.83) | PDE4B | |
| SCHEMBL4336374 | 0.89 | PDE4B (0.98) | PDE4B | |
| SCHEMBL4350690 | 0.89 | PDE4B (0.83) | PDE4B | |
| SCHEMBL14115726 | 0.89 | PDE4B (0.82) | PDE4B | |
| SCHEMBL2771365 | 0.89 | PDE4B (0.73) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528148-B2 | Pyrazolo[3,4-B]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |