Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865615 | 0.91 | NPC1 (0.43) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL13865597 | 0.91 | NPC1 (0.43) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL13865620 | 0.90 | NPC1 (0.38) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL13806742 | 0.88 | PLA2G4B (0.43) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL15293312 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL13380171 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL15293305 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL15293320 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL15284731 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 | |
| SCHEMBL15293315 | 0.85 | HTT (0.48) | LSSHTTNPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527746-B2 | Liquid crystal polyfunctional acrylate derivative and polymer thereof | CHISSO CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |
| US-7527746-B2 | Liquid crystal polyfunctional acrylate derivative and polymer thereof | CHISSO CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |