Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.62 |
| ▸ | FAP | Q12884 | 7/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3888330 | 0.93 | DPP4 (0.55) | DPP4FAPDPP9 | |
| SCHEMBL13866854 | 0.87 | DPP4 (0.57) | DPP4FAPDPP9 | |
| SCHEMBL13866862 | 0.86 | DPP4 (0.57) | DPP4FAPDPP9 | |
| SCHEMBL13866851 | 0.86 | DPP4 (0.57) | DPP4FAPDPP9 | |
| SCHEMBL13866841 | 0.83 | DPP4 (0.59) | DPP4FAPDPP9 | |
| SCHEMBL13866863 | 0.83 | DPP4 (0.61) | DPP4FAPDPP9PKM | |
| SCHEMBL13866858 | 0.82 | DPP4 (0.53) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL3874619 | 0.81 | DPP4 (0.51) | DPP4FAPDPP9 | |
| SCHEMBL13866847 | 0.81 | DPP4 (0.56) | DPP4FAPDPP9 | |
| SCHEMBL13866856 | 0.81 | DPP4 (0.54) | DPP4FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |