Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.47 |
| ▸ | FAP | Q12884 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3879206 | 0.92 | DPP4 (0.41) | DPP4FAPDPP9KCNH2 | |
| SCHEMBL13866885 | 0.91 | DPP4 (0.47) | DPP4FAPDPP9KCNH2 | |
| SCHEMBL13866882 | 0.88 | DPP4 (0.50) | DPP4FAPDPP9KCNH2 | |
| SCHEMBL13866842 | 0.87 | DPP4 (0.61) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL3883168 | 0.83 | DPP4 (0.41) | DPP4FAPALDH1A1DPP9KCNH2 | |
| SCHEMBL13866893 | 0.83 | DPP4 (0.45) | DPP4FAPDPP9 | |
| SCHEMBL13866884 | 0.83 | DPP4 (0.45) | DPP4FAPDPP9 | |
| SCHEMBL13866888 | 0.82 | DPP4 (0.45) | DPP4FAPDPP9 | |
| SCHEMBL13866887 | 0.82 | DPP4 (0.56) | DPP4FAPALDH1A1CYP1A2HPGD | |
| SCHEMBL13866891 | 0.82 | DPP4 (0.60) | DPP4FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |