Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.45 |
| ▸ | FAP | Q12884 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3881058 | 0.95 | DPP4 (0.43) | DPP4FAPDPP9L3MBTL1P2RX3 | |
| SCHEMBL13875681 | 0.89 | DPP4 (0.42) | DPP4L3MBTL1P2RX3 | |
| SCHEMBL13866891 | 0.85 | DPP4 (0.60) | DPP4FAPDPP9P2RX3 | |
| SCHEMBL3881063 | 0.83 | DPP4 (0.42) | DPP4FAPDPP9L3MBTL1P2RX3 | |
| Trifluoroacetic Acid SCHEMBL3885741 | 0.83 | DPP4 (0.53) | DPP4FAPDPP9P2RX3 | |
| SCHEMBL13866888 | 0.82 | DPP4 (0.45) | DPP4FAPDPP9L3MBTL1P2RX3 | |
| Trifluoroacetic Acid SCHEMBL3884728 | 0.82 | DPP4 (0.46) | DPP4FAPDPP9L3MBTL1P2RX3 | |
| SCHEMBL13866887 | 0.80 | DPP4 (0.56) | DPP4FAPDPP9 | |
| SCHEMBL13866884 | 0.80 | DPP4 (0.45) | DPP4FAPDPP9P2RX3 | |
| SCHEMBL13866882 | 0.78 | DPP4 (0.50) | DPP4FAPDPP9P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |