Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.73 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.73 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13867466 | 1.00 | CARM1 (0.73) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL1267683 | 1.00 | CARM1 (0.73) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL23768688 | 0.98 | CARM1 (0.70) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL1268626 | 0.98 | CARM1 (0.70) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL2356698 | 0.98 | CARM1 (0.70) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7255511 | 0.95 | CARM1 (0.67) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL1663805 | 0.95 | — | — | |
| SCHEMBL4342747 | 0.93 | CARM1 (0.70) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL17519179 | 0.91 | CARM1 (0.61) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 | |
| SCHEMBL2687491 | 0.91 | CARM1 (0.67) | CARM1PRMT6PRMT8HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517913-B2 | Polyamine conjugates with acidic retinoids and preparation thereof | PAPAIOANNOU DIONYSIOS | 2009-04-14 | — | — | US | disclosed |