Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.56 |
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909016 | 0.90 | PTPN1 (0.61) | PTPN1PTPN2PTPRC | |
| SCHEMBL3910849 | 0.89 | PTPN1 (0.77) | PTPN1PTPN2PTPRC | |
| SCHEMBL3915438 | 0.89 | PTPN1 (0.68) | PTPN1PTPN2PTPRC | |
| SCHEMBL3906558 | 0.89 | PTPN1 (0.74) | PTPN1PTPN2PTPRC | |
| SCHEMBL3906597 | 0.88 | PTPN1 (0.71) | PTPN1PTPN2PTPRC | |
| SCHEMBL3911698 | 0.88 | PTPN1 (0.77) | PTPN1PTPN2PTPRC | |
| SCHEMBL3916849 | 0.87 | PTPN1 (0.57) | PTPN1PTPN2PTPRC | |
| SCHEMBL25036632 | 0.85 | PTPN1 (0.55) | PTPN1PTPN2PTPRC | |
| SCHEMBL3909802 | 0.84 | PTPN1 (0.65) | PTPN1PTPN2PTPRC | |
| SCHEMBL6263476 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |