Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.71 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.66 |
| ▸ | PTPRC | P08575 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3906624 | 0.95 | PTPN1 (0.79) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907417 | 0.94 | PTPN1 (0.70) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3911951 | 0.92 | PTPN1 (0.68) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3903963 | 0.89 | PTPN1 (0.74) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908145 | 0.88 | PTPN1 (0.75) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3904970 | 0.87 | PTPN1 (0.66) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906886 | 0.87 | PTPN1 (0.66) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6272179 | 0.87 | PTPN1 (0.62) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL6272173 | 0.86 | PTPN1 (0.61) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3916887 | 0.85 | PTPN1 (0.64) | PTPN1PTPN2PTPRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |