Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC9A3 | P48764 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713241 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL13359968 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL614427 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL14982786 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL13572033 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL16349763 | 1.00 | PDE4A (0.56) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| Water SCHEMBL28832904 | 0.98 | PDE4A (0.54) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| Ammonia Solution, Strong SCHEMBL27853962 | 0.98 | PDE4A (0.54) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL3125161 | 0.93 | KDM4E (0.46) | PDE4ALMNAKDM4EL3MBTL1TDP1 | |
| SCHEMBL19233364 | 0.93 | KDM4E (0.46) | PDE4ALMNAKDM4EL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |