Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.69 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895960 | 0.96 | CALCRL (0.74) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2167063 | 0.96 | CALCRL (0.72) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13181377 | 0.92 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2165540 | 0.92 | CALCRL (0.78) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13895746 | 0.91 | CALCRL (0.62) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13895750 | 0.90 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13895749 | 0.90 | CALCRL (0.64) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13895961 | 0.90 | CALCRL (0.61) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2166862 | 0.89 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL2164285 | 0.89 | CALCRL (0.68) | CALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528129-B2 | CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-05 | — | — | US | disclosed |