Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386457 | 0.96 | SSTR5 (0.39) | SSTR5KCNH2CSNK1DCSNK1EHRH2 | |
| SCHEMBL2926287 | 0.88 | NPY5R (0.41) | SSTR5KCNH2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL2926317 | 0.85 | NPY5R (0.40) | SSTR5KCNH2CSNK1DCSNK1EMAPK14 | |
| SCHEMBL1385679 | 0.83 | MAPK14 (0.39) | KCNH2CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL2929523 | 0.81 | MAPK14 (0.39) | KCNH2CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL1386590 | 0.80 | NPC1 (0.40) | KCNH2CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL29652668 | 0.80 | CSNK1D (0.38) | KCNH2CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL1386122 | 0.79 | MAPK14 (0.48) | KCNH2CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL1383826 | 0.79 | MAPK14 (0.39) | CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL2929529 | 0.78 | MAPK14 (0.52) | CSNK1DCSNK1EMAPK14MAPK11RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4814783-B2 | — | — | 2011-11-16 | — | — | JP | claimed |
| EP-1611131-A1 | PYRAZOLOPYRIDINE DERIVATES | J. Uriach y Compagnia S.A. (ES) | 2006-01-04 | — | — | EP | claimed |
| WO-2004076450-A1 | PYRAZOLOPYRIDINE DERIVATES | J. Uriach Y Compañia S.A. (ES) | 2004-09-10 | — | — | WO | claimed |