Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386098 | 0.86 | F10 (0.42) | F10KCNH2AKR1B1CNR1 | |
| SCHEMBL1386482 | 0.84 | F10 (0.45) | F10KCNH2AKR1B1CNR1KLK1 | |
| SCHEMBL1385219 | 0.82 | F10 (0.43) | F10KCNH2AKR1B1CNR1KLK1 | |
| SCHEMBL1387034 | 0.77 | F10 (0.48) | F10KCNH2AKR1B1KLK1 | |
| SCHEMBL1385578 | 0.73 | F10 (0.47) | F10KCNH2KLK1 | |
| SCHEMBL1386569 | 0.73 | F10 (0.57) | F10KCNH2 | |
| SCHEMBL4387457 | 0.73 | F10 (0.57) | F10KCNH2 | |
| SCHEMBL1387135 | 0.73 | F10 (0.57) | F10KCNH2 | |
| SCHEMBL4392578 | 0.71 | KCNH2 (0.35) | F10KCNH2 | |
| SCHEMBL6421791 | 0.70 | USP2 (0.57) | F10AKR1B1CNR1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |