Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869756 | 0.98 | MAPT (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869755 | 0.97 | MAPT (0.54) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869750 | 0.93 | CYP19A1 (0.57) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869700 | 0.93 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869745 | 0.92 | CYP19A1 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869760 | 0.90 | CYP19A1 (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869759 | 0.89 | CYP19A1 (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869710 | 0.88 | CYP19A1 (0.60) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869675 | 0.88 | CYP19A1 (0.60) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13869692 | 0.87 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |