Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13869807 | 0.88 | CYP19A1 (0.61) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869318 | 0.87 | CYP19A1 (0.70) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869801 | 0.86 | CYP19A1 (0.59) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869806 | 0.84 | CYP19A1 (0.57) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869771 | 0.84 | CYP19A1 (0.68) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869800 | 0.83 | CYP19A1 (0.56) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869776 | 0.82 | CYP19A1 (0.55) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869786 | 0.81 | CYP19A1 (0.53) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13886436 | 0.81 | CYP19A1 (0.53) | CYP19A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13869685 | 0.81 | CYP19A1 (0.58) | CYP19A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |