Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477695 | 0.94 | PIK3CD (0.59) | PIK3CD | |
| SCHEMBL12600957 | 0.76 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL14342239 | 0.76 | PIK3CD (0.53) | PIK3CDL3MBTL1 | |
| SCHEMBL12248384 | 0.76 | — | — | |
| SCHEMBL2755782 | 0.75 | PIK3CD (0.88) | PIK3CDL3MBTL1 | |
| SCHEMBL10426939 | 0.73 | PIK3CD (0.85) | PIK3CDL3MBTL1 | |
| SCHEMBL18020611 | 0.73 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL867810 | 0.73 | PIK3CD (0.85) | PIK3CDL3MBTL1 | |
| SCHEMBL26863347 | 0.73 | PIK3CD (0.85) | PIK3CDL3MBTL1 | |
| SCHEMBL19762037 | 0.72 | HRH3 (0.32) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528148-B2 | Pyrazolo[3,4-B]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |