Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | ALB | P02768 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870886 | 0.88 | KMT2A (0.80) | POLBALBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL34615 | 0.84 | MEN1 (0.73) | POLBTSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL13870890 | 0.83 | ALB (1.00) | ALBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13870899 | 0.82 | TP53 (0.81) | POLBALBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL13870923 | 0.78 | KMT2A (0.98) | POLBTSHRALDH1A1SMN1; SMN2CREBBP | |
| SCHEMBL13870919 | 0.78 | KMT2A (1.00) | POLBTSHRALDH1A1SMN1; SMN2CREBBP | |
| SCHEMBL13532208 | 0.76 | ALB (0.82) | POLBALBALDH1A1MEN1KMT2A | |
| SCHEMBL3919968 | 0.73 | TSHR (0.74) | TSHRALDH1A1SMN1; SMN2MAPK1CREBBP | |
| SCHEMBL6348773 | 0.73 | ALB (0.80) | ALBALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6353213 | 0.73 | ALB (0.80) | ALBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | 7TM PHARMA A/S (DK) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105218-A1 | CRTH2 Receptor Ligands For Therapeutic Use | NR1H2, NR1H3, HRH2 | POLB 4251/4885ALB 3957/4885TSHR 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.