Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.59 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873825 | 0.90 | EPHX2 (0.55) | EPHX2CYP2C9CYP2J2LIPECHRNA7 | |
| SCHEMBL13873771 | 0.87 | EPHX2 (0.57) | EPHX2CYP2C9CYP2J2LIPECHRNA7 | |
| SCHEMBL13873763 | 0.87 | EPHX2 (0.61) | EPHX2CYP2C9CYP2J2LIPECHRNA7 | |
| SCHEMBL13874900 | 0.85 | EPHX2 (0.52) | EPHX2CYP2C9CYP2J2LIPECHRNA7 | |
| SCHEMBL13873844 | 0.81 | CYP2C9 (0.58) | EPHX2CYP2C9CYP2J2CHRNA7KIT | |
| SCHEMBL13873859 | 0.78 | MEN1 (0.54) | CYP2C9KITNAMPT | |
| SCHEMBL13873786 | 0.78 | EPHX2 (0.69) | EPHX2CYP2C9CYP2J2CHRNA7KIT | |
| SCHEMBL13873620 | 0.78 | EPHX2 (0.61) | EPHX2CYP2C9CYP2J2CHRNA7 | |
| SCHEMBL13873833 | 0.77 | CYP2C9 (0.57) | EPHX2CYP2C9CYP2J2CHRNA7KIT | |
| SCHEMBL13873755 | 0.76 | EPHX2 (0.57) | EPHX2CYP2C9CYP2J2CHRNA7KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | US | disclosed |
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111791-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885CYP2C9 477/4885CYP2J2 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.