SCHEMBL1387474

SCHEMBL1387474

O=C(CNS(=O)(=O)c1ccc2ccccc2c1)NCC(NC(=O)CN1CCN(c2ccncc2)CC1)C(=O)N1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.46
PLG P00747 1/20 0.45
PLAU P00749 1/20 0.45
F2 P00734 3/20 0.43
HTR7 P34969 3/20 0.43
PKM P14618 1/20 0.42
CTSS P25774 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387470 0.97 F10 (0.46) F10PLGPLAUF2HTR7
SCHEMBL7403416 0.92 F10 (0.47) F10PLGPLAUF2HTR7
SCHEMBL6789447 0.89 F10 (0.48) F10PLGPLAUF2HTR7
SCHEMBL6792769 0.88 F10 (0.54) F10PLGPLAUF2PKM
SCHEMBL7402407 0.88 F10 (0.54) F10PLGPLAUF2PKM
SCHEMBL1387300 0.87 F10 (0.54) F10PLGPLAUF2
SCHEMBL6793666 0.86 F10 (0.55) F10PLGPLAUF2
SCHEMBL6786184 0.84 F10 (0.49) F10PLGPLAUF2HTR7
SCHEMBL7123827 0.83 F10 (0.49) F10PLGPLAUF2
SCHEMBL6798932 0.80 F10 (0.57) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-H10506122-A 1998-06-16 JP claimed
EP-0783500-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1997-07-16 EP claimed
WO-1996010022-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1996-04-04 WO claimed
EP-0783500-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1997-07-16 EP disclosed
WO-1996010022-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1996-04-04 WO disclosed