Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.82 |
| ▸ | MAOA | P21397 | 2/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340616 | 0.92 | DYRK1A (0.88) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL17517549 | 0.91 | DYRK1A (0.69) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL668477 | 0.90 | DYRK1A (1.00) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL28590131 | 0.89 | DYRK1A (0.79) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL17517503 | 0.89 | DYRK1A (0.88) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL13875060 | 0.89 | HASPIN (0.88) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL17502363 | 0.88 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL17502361 | 0.88 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL3857445 | 0.88 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL17517505 | 0.88 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050747-A1 | Dimers of harmol or of its derivatives and uses thereof | BioAlliance Pharma (FR) | 2009-04-22 | — | — | EP | disclosed |