Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387528 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL3188369 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Hydrochloric Acid SCHEMBL2552365 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Hydrochloric Acid SCHEMBL10650843 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Hydrochloric Acid SCHEMBL27475495 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10430005 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Water SCHEMBL10587049 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Hydrochloric Acid SCHEMBL10650848 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Water SCHEMBL10587053 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| Hydrochloric Acid SCHEMBL2552367 | 0.98 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117904246-A | Preparation method of antibiotic cephalosporin nucleus | 浙江普洛得邦制药有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-110294770-A | A kind of cephalosporanic olefinic salt compound, preparation method and in the method for the compound synthesis Cefquinome | 齐鲁晟华制药有限公司 | 2019-10-01 | — | — | CN | claimed |
| CN-107353297-A | A kind of efficient Ceftaroline Fosamil synthetic method | 郑州大学 | 2017-11-17 | — | — | CN | claimed |
| CN-104725425-B | A kind of preparation method of Ceftaroline Fosamil | 山东罗欣药业集团股份有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-102372728-B | Synthesizing method for cephalosporin compound | QILU ANTIBIOTICS PHARMACEUTICAL CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-102703559-B | Preparation method for 7 beta-amino-3-[4-(1-methyl-4-pyridinium)-2-thiazole sulfenyl]-3-cephem-4-carboxylate acidification matter | SHANDONG CHENGCHUANG MEDICAL TECHNOLOGY DEV CO LTD | 2013-09-11 | — | — | CN | claimed |
| CN-102234289-B | Novel method for preparing ceftiofur intermediate | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-07-10 | — | — | CN | claimed |
| CN-101654458-B | Preparation method of hydrochloric acid ceftiofur | LUOYANG PU LIKE BIOENGINEERING CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-102286000-A | Preparation method of cefonicid and medicinal salts thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-102234289-A | Novel method for preparing ceftiofur intermediate | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2011-11-09 | — | — | CN | claimed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | claimed |
| US-4399278-A | 7-AMINO-2 OR 3-CEPHEM-4-CARBOXY COMPOUNDS HAVING ANTIBACTERIAL PROPERTIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | claimed |
| EP-0021688-B1 | 7-(THIAZOLYLPROPIONAMIDO) CEPHALOSPORINS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-07-13 | — | — | EP | claimed |
| EP-0010313-B1 | 3,7-DISUBSTITUTED-2- OR -3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-26 | — | — | EP | claimed |
| US-4342757-A | Cephalosporin antibiotic compositions | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | claimed |
| EP-0000272-B1 | 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1982-05-05 | — | — | EP | claimed |
| US-4327093-A | TREATING INFECTIONS DISEASES, ANTIBACTERIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-27 | — | — | US | claimed |
| EP-0042154-A1 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-23 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| EP-0010313-A1 | 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | claimed |