⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4539695 | 0.97 | — | — | |
| SCHEMBL5727449 | 0.74 | — | — | |
| SCHEMBL10433552 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8987314 | 0.65 | — | — | |
| SCHEMBL7480588 | 0.58 | — | — | |
| SCHEMBL18656543 | 0.55 | — | — | |
| SCHEMBL1755914 | 0.54 | — | — | |
| SCHEMBL9976125 | 0.54 | — | — | |
| SCHEMBL4228701 | 0.51 | — | — | |
| SCHEMBL4394267 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H09504278-A | — | — | 1997-04-28 | — | — | JP | claimed |
| EP-0723438-A1 | SUBSTITUTED UREA AND ISOTHIOUREA DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-31 | — | — | EP | claimed |
| EP-0713704-A1 | 2-Amino-1,3-thiazines as nitric oxide synthase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995009619-A2 | SUBSTITUTED UREA AND ISOTHIOUREA DERIVATIVES AS NO SYNTHASE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-13 | — | — | WO | claimed |
| US-4049807-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | claimed |
| JP-8239369-A | — | — | None | — | — | JP | disclosed |
| US-12590963-B2 | Anti-cancer treatment of preselected subjects and screening methods to identify susceptible subjects | TUDAG TU DRESDEN AKTIENGESELLSCHAFT (DE) | 2026-03-31 | — | — | US | disclosed |
| EP-2956458-A1 | HETEROARYL-SUBSTITUTED HEXAHYDROPYRANO [3,4-d][1,3]THIAZIN-2-AMINE COMPOUNDS | Pfizer Inc. (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2935256-A1 | 4,6-DIARYLAMINOTHIAZINES AS BACE1 INHIBITORS AND THEIR USE FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | Bristol-Myers Squibb Company (US) | 2015-10-28 | — | — | EP | disclosed |
| US-9045499-B2 | Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | PFIZER INC. (US) | 2015-06-02 | — | — | US | disclosed |
| WO-2015017407-A1 | BRIDGED BICYCLIC AMINO THIAZINE DIOXIDE COMPOUNDS AS INHIBITORS OF BETA- SECRETASE | AMGEN INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-20140364426-A1 | Heteroaryl-Substituted Hexahydropyrano[3,4-d][1,3]Thiazin-2-Amine Compounds | PFIZER (US) | 2014-12-11 | — | — | US | disclosed |
| EP-0713704-A1 | 2-Amino-1,3-thiazines as nitric oxide synthase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-29 | — | — | EP | disclosed |
| EP-0713704-A1 | 2-Amino-1,3-thiazines as nitric oxide synthase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-29 | — | — | EP | disclosed |
| US-5500406-A | 1-AZOLYLIDENEIMINIOSULFONYL-3-PYRIMIDIN-2-YL UREAS; LOW DOSAGE; HIGH SELECTIVITY; CROPS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0592676-A1 | IMINOSULFONYLUREA DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-4054652-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1977-10-18 | — | — | US | disclosed |
| US-4049807-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4049807-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4049807-A | FUNGICIDE, BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |