Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.48 |
| ▸ | PTPRC | P08575 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13867890 | 0.91 | PTPN1 (0.49) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907448 | 0.91 | PTPN1 (0.54) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3909646 | 0.89 | PTPN1 (0.58) | PTPN1PTPRCPTPN2 | |
| SCHEMBL13867883 | 0.88 | PTPN1 (0.51) | PTPN1PTPRCPTPN2 | |
| SCHEMBL6261791 | 0.88 | PTPN1 (0.43) | PTPN1PTPRCPTPN2 | |
| SCHEMBL13867884 | 0.88 | PTPN1 (0.48) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3915222 | 0.87 | PTPN1 (0.50) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3908176 | 0.87 | PTPN1 (0.50) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3916561 | 0.87 | PTPN1 (0.44) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3905661 | 0.86 | PTPN1 (0.49) | PTPN1PTPRCPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |