Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878602 | 1.00 | TLR2 (0.54) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878676 | 1.00 | TLR2 (0.54) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878621 | 1.00 | TLR2 (0.54) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878683 | 0.99 | TLR2 (0.53) | TLR2KMT2ATNFMDM2CASP3 | |
| SCHEMBL13878675 | 0.96 | KMT2A (0.50) | TLR2KMT2ATNFMDM2CASP3 | |
| SCHEMBL13878682 | 0.92 | KMT2A (0.52) | TLR2KMT2ACASP3 | |
| SCHEMBL13878630 | 0.90 | KMT2A (0.48) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878608 | 0.89 | KMT2A (0.47) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878836 | 0.88 | KMT2A (0.46) | TLR2KMT2ATNFHDAC1HDAC2 | |
| SCHEMBL13878669 | 0.88 | KMT2A (0.54) | KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | SLC1A2, NR1H4, OXGR1 | TLR2 1377/4885KMT2A 1541/4885TNF 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.