Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 8/20 | 0.46 |
| ▸ | BCR | P11274 | 6/20 | 0.46 |
| ▸ | HCK | P08631 | 4/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | LYN | P07948 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878751 | 0.93 | CSF1R (0.57) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878727 | 0.92 | CSF1R (0.59) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878748 | 0.88 | LYN (0.48) | CSF1RABL1BCRHCKLCK | |
| SCHEMBL13878730 | 0.87 | LCK (0.55) | CSF1RHCKLCKLYNSRC | |
| SCHEMBL13878752 | 0.85 | CSF1R (0.57) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878725 | 0.84 | CSF1R (0.63) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878750 | 0.83 | ABL1 (0.56) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878806 | 0.82 | CSF1R (0.61) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL13878753 | 0.82 | CSF1R (0.56) | CSF1RKDM4EPOLBRECQLMAPT | |
| SCHEMBL1704685 | 0.81 | RAF1 (0.54) | CSF1RABL1BCRHCKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105250-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-04-23 | — | — | US | disclosed |
| US-20090105250-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105250-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | ABL1, BCR, PDGFRB | CSF1R 891/4885KDM4E 2668/4885POLB 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.