Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664965 | 0.89 | SMN1; SMN2 (0.55) | F10SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL13290428 | 0.88 | F10 (0.61) | F10SMN1; SMN2RAB9AMAPK1LMNA | |
| SCHEMBL2953281 | 0.88 | SMN1; SMN2 (0.48) | F10SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL2953282 | 0.88 | SMN1; SMN2 (0.48) | F10SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL13290955 | 0.88 | SMN1; SMN2 (0.44) | F10SMN1; SMN2RAB9AMAPK1LMNA | |
| SCHEMBL13290946 | 0.87 | SMN1; SMN2 (0.43) | F10SMN1; SMN2RAB9AMAPK1LMNA | |
| SCHEMBL2950971 | 0.86 | SMN1; SMN2 (0.48) | F10SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL2950956 | 0.86 | SMN1; SMN2 (0.48) | F10SMN1; SMN2RAB9ALMNATSHR | |
| SCHEMBL13291017 | 0.86 | F10 (0.47) | F10SMN1; SMN2RAB9AMAPK1LMNA | |
| SCHEMBL13290417 | 0.86 | SMN1; SMN2 (0.46) | F10SMN1; SMN2RAB9ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |