⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323702 | 1.00 | — | — | |
| SCHEMBL19619209 | 1.00 | — | — | |
| SCHEMBL13873340 | 1.00 | — | — | |
| SCHEMBL16882152 | 1.00 | — | — | |
| SCHEMBL17320695 | 0.91 | — | — | |
| SCHEMBL19619249 | 0.91 | — | — | |
| SCHEMBL17323421 | 0.91 | — | — | |
| SCHEMBL13890139 | 0.91 | — | — | |
| SCHEMBL17323725 | 0.91 | — | — | |
| SCHEMBL13873332 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390255-A1 | Novel aminoglycosides and uses thereof in the treatment of genetic disorders | Technion Research & Development Foundation Limited (IL) | 2011-11-30 | — | — | EP | disclosed |
| US-20090093418-A1 | Novel aminoglycosides and uses thereof in the treatment of genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-04-09 | — | — | US | disclosed |