SCHEMBL1389333

SCHEMBL1389333

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nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14408817 1.00
SCHEMBL10039216 0.80
SCHEMBL15298263 0.80
SCHEMBL4919959 0.79 HSD17B10 (0.35)
SCHEMBL7971977 0.79 HSD17B10 (0.35)
SCHEMBL571275 0.79 AKR1B1 (0.35)
SCHEMBL27383307 0.79 HSD17B10 (0.35)
Formaldehyde SCHEMBL3166767 0.74 MAPT (0.32)
SCHEMBL2839162 0.73
SCHEMBL2218041 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981844-B2 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes VERENIUM CORPORATION (US) 2011-07-19 US claimed
EP-1654371-A2 METHODS FOR THE MANUFACTURE OF PURE SINGLE ENANTIOMER COMPOUNDS AND FOR SELECTING ENANTIOSELECTIVE ENZYMES Diversa Corporation (US) 2006-05-10 EP claimed
US-20030092033-A1 Methods for the Manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes VERENIUM CORPORATION 2003-05-15 US claimed
WO-2003000909-A2 METHODS FOR THE MANUFACTURE OF PURE SINGLE ENANTIOMER COMPOUNDS AND FOR SELECTING ENANTIOSELECTIVE ENZYMES DIVERSA CORPORATION (US) 2003-01-03 WO claimed
US-20120010104-A1 GROWTH SELECTION METHOD VERENIUM CORPORATION 2012-01-12 US disclosed
US-7981844-B2 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes VERENIUM CORPORATION (US) 2011-07-19 US disclosed
EP-1654371-A2 METHODS FOR THE MANUFACTURE OF PURE SINGLE ENANTIOMER COMPOUNDS AND FOR SELECTING ENANTIOSELECTIVE ENZYMES Diversa Corporation (US) 2006-05-10 EP disclosed
US-20030092033-A1 Methods for the Manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes VERENIUM CORPORATION 2003-05-15 US disclosed
WO-2003000909-A2 METHODS FOR THE MANUFACTURE OF PURE SINGLE ENANTIOMER COMPOUNDS AND FOR SELECTING ENANTIOSELECTIVE ENZYMES DIVERSA CORPORATION (US) 2003-01-03 WO disclosed