Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.67 |
| ▸ | CLK2 | P49760 | 1/20 | 0.67 |
| ▸ | MTTP | P55157 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894012 | 0.93 | BTK (0.78) | BTKCLK2 | |
| SCHEMBL13894051 | 0.93 | BTK (0.67) | BTKCLK2TYK2 | |
| SCHEMBL13894124 | 0.92 | BTK (0.65) | BTKCLK2TYK2 | |
| SCHEMBL13894056 | 0.91 | BTK (0.68) | BTKCLK2 | |
| SCHEMBL13894115 | 0.90 | BTK (0.63) | BTKCLK2 | |
| SCHEMBL3867480 | 0.87 | BTK (0.88) | BTKCLK2 | |
| SCHEMBL1322606 | 0.84 | BTK (0.77) | BTKCLK2 | |
| SCHEMBL13894025 | 0.83 | BTK (0.67) | BTKCLK2 | |
| SCHEMBL3892201 | 0.82 | BTK (0.90) | BTKCLK2 | |
| SCHEMBL3872827 | 0.82 | BTK (0.86) | BTKCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053269-A1 | NOVEL KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | disclosed |