Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | PDE8A | O60658 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040220 | 0.82 | CDK1 (0.66) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL129921 | 0.81 | CDK1 (1.00) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL22700335 | 0.81 | CDK1 (0.64) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL27983442 | 0.79 | CDK1 (0.59) | CDK1ADORA2AADORA1HSP90AA1HSP90B1 | |
| SCHEMBL23619320 | 0.78 | CDK1 (0.60) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL15789757 | 0.78 | CDK1 (0.50) | CDK1HSP90AA1 | |
| SCHEMBL12702726 | 0.77 | CDK1 (0.63) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL22700151 | 0.77 | CDK1 (0.63) | CDK1CFTRADORA3ADORA2AADORA1 | |
| SCHEMBL3441256 | 0.77 | CDK2 (0.71) | CDK1ADORA3ADORA2AADORA1PDE8A | |
| SCHEMBL27635727 | 0.77 | CDK1 (0.58) | CDK1CFTRADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010397-A1 | Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN LTD. | 2012-01-12 | — | — | US | disclosed |
| EP-2404926-A1 | Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-adenine | ScinoPharm Taiwan, Ltd. (TW) | 2012-01-11 | — | — | EP | disclosed |
| EP-0755255-A4 | TREATMENT OF TOXOPLASMOSIS | RES CORP TECHNOLOGIES INC (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1177202-A1 | 4'-C-ETHYNYL PURINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2002-02-06 | — | — | EP | disclosed |
| US-6333315-B1 | FOR THERAPY OF AIDS(ACQUIRE IMMUNODEFICIENCY SYNDROME) | YAMASA CORPORATION (JP) | 2001-12-25 | — | — | US | disclosed |
| WO-2000069877-A1 | 4'-C-ETHYNYL PURINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2000-11-23 | — | — | WO | disclosed |
| EP-0755255-A1 | TREATMENT OF TOXOPLASMOSIS | UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996018398-A1 | TREATMENT OF TOXOPLASMOSIS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010397-A1 | Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine | HPRT1, TYMP, MTAP | CDK1 1500/4885CFTR 2625/4885ADORA3 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.