Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487700 | 0.94 | PTGER1 (0.57) | PTGER1THRBNPSR1MEN1KMT2A | |
| SCHEMBL13894465 | 0.91 | PTGER1 (0.51) | PTGER1THRBNPSR1 | |
| SCHEMBL2175531 | 0.89 | PTGER1 (0.55) | PTGER1THRBNPSR1OXTRMEN1 | |
| SCHEMBL12482052 | 0.85 | PTGER1 (0.66) | PTGER1THRB | |
| SCHEMBL13894183 | 0.85 | PTGER1 (0.56) | PTGER1THRBOXTRMEN1KMT2A | |
| SCHEMBL2174802 | 0.85 | PTGER1 (0.54) | PTGER1THRBNPSR1OXTRMEN1 | |
| SCHEMBL2176713 | 0.84 | PTGER1 (0.61) | PTGER1THRB | |
| SCHEMBL12407255 | 0.84 | PTGER1 (0.64) | PTGER1THRBOXTR | |
| SCHEMBL12407161 | 0.84 | PTGER1 (0.76) | PTGER1THRBMEN1KMT2A | |
| SCHEMBL13894262 | 0.83 | PTGER1 (0.63) | PTGER1THRBNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050446-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-04-22 | — | — | EP | disclosed |