Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940454 | 0.98 | PLA2G2C (0.48) | PLA2G2CFFAR4FFAR1PLA2G10ALDH1A1 | |
| SCHEMBL11665886 | 0.93 | PLA2G2C (0.49) | PLA2G2CFFAR4FFAR1PLA2G10ALDH1A1 | |
| SCHEMBL11021921 | 0.88 | PLA2G2C (0.64) | PLA2G2CFFAR4FFAR1PLA2G10ALDH1A1 | |
| SCHEMBL27566548 | 0.86 | PLA2G2C (0.61) | PLA2G2CFFAR4FFAR1PLA2G10ALDH1A1 | |
| SCHEMBL1479318 | 0.85 | PLA2G2C (0.55) | PLA2G2CPLA2G10ALOX15 | |
| SCHEMBL3503915 | 0.83 | PLA2G2C (0.54) | PLA2G2CPLA2G10ALOX15 | |
| SCHEMBL13840537 | 0.83 | PLA2G2C (0.60) | PLA2G2CFFAR1GPR84 | |
| SCHEMBL8513712 | 0.81 | PLA2G2C (0.57) | PLA2G2CFFAR1GPR84 | |
| SCHEMBL11546042 | 0.79 | ANPEP (0.50) | PLA2G2CFFAR4FFAR1ALDH1A1GPR84 | |
| SCHEMBL13715798 | 0.79 | PLA2G2C (0.59) | PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042544-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |