Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895489 | 0.93 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895461 | 0.92 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895413 | 0.91 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895434 | 0.91 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895416 | 0.91 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895460 | 0.90 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895415 | 0.88 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1 | |
| SCHEMBL3523057 | 0.87 | HSP90AA1 (0.81) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895435 | 0.85 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1 | |
| SCHEMBL13731293 | 0.85 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012148550-A1 | PRODRUGS OF THERAPEUTIC COMPOUNDS | MYREXIS, INC. (US) | 2012-11-01 | — | — | WO | disclosed |