⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773524 | 0.67 | — | — | |
| SCHEMBL18932499 | 0.62 | — | — | |
| SCHEMBL15001017 | 0.62 | — | — | |
| SCHEMBL917879 | 0.62 | — | — | |
| SCHEMBL2505546 | 0.60 | — | — | |
| SCHEMBL13645479 | 0.58 | — | — | |
| SCHEMBL15001015 | 0.58 | — | — | |
| SCHEMBL5301971 | 0.57 | — | — | |
| SCHEMBL18792330 | 0.57 | — | — | |
| SCHEMBL17080877 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987453-B2 | Azaadamantane derivatives and methods of use | ABBVIE INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130096132-A1 | AZAADAMANTANE DERIVATIVES AND METHODS OF USE | ABBVIE INC. (US) | 2013-04-18 | — | — | US | disclosed |
| US-8314119-B2 | Azaadamantane derivatives and methods of use | ABBVIE INC. (US) | 2012-11-20 | — | — | US | disclosed |
| US-20080167336-A1 | Alzheimer's disease; central nervous system disorders; aids; Pick's disease; attention deficit disorder; hyperactivity; Down's syndrome, amytropic lateral sclerosis; Huntington's disease; suppression of smoking; drug abruse; brain disorders; analgesics; antiinflammatory agents | ABBOTT LABORATORIES (US) | 2008-07-10 | — | — | US | disclosed |