Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896349 | 0.95 | ADRB3 (0.47) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12652957 | 0.95 | ADRB3 (0.52) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12618532 | 0.95 | ADRB3 (0.52) | ADRB3ADRA2BADRA2C | |
| SCHEMBL13892482 | 0.92 | ADRB3 (0.50) | ADRB3ADRA2BADRA2C | |
| SCHEMBL14001907 | 0.88 | ADRB3 (0.49) | ADRB3ADRA2BADRA2C | |
| SCHEMBL13896390 | 0.88 | ADRB3 (0.44) | ADRB3ADRA2BADRA2C | |
| SCHEMBL13886255 | 0.87 | ADRB3 (0.53) | ADRB3ADRA2BADRA2C | |
| SCHEMBL3975287 | 0.86 | ADRB3 (0.48) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8278094 | 0.86 | ADRB3 (0.48) | ADRB3ADRA2BADRA2C | |
| SCHEMBL3975284 | 0.86 | ADRB3 (0.48) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680137-B1 | Macrocyclic carboxylic acid and acylsulfonamide compound as inhibitor of HCV replication | HOFFMANN LA ROCHE (CH) | 2012-11-21 | — | — | EP | disclosed |