Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 18/20 | 0.72 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647227 | 0.98 | CMA1 (0.75) | CMA1CTSGKDM4EHSD17B10PLA2G2A | |
| SCHEMBL3647231 | 0.98 | CMA1 (0.75) | CMA1CTSGKDM4EHSD17B10PLA2G2A | |
| SCHEMBL3647364 | 0.86 | CMA1 (0.81) | CMA1CTSG | |
| SCHEMBL3647361 | 0.86 | CMA1 (0.81) | CMA1CTSG | |
| SCHEMBL3650123 | 0.86 | CMA1 (0.81) | CMA1CTSG | |
| SCHEMBL2696330 | 0.84 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2697085 | 0.84 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2696326 | 0.84 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2699632 | 0.80 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2698223 | 0.80 | CMA1 (1.00) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188277-B1 | QUINAZOLINEDIONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-11-21 | — | — | EP | disclosed |