Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.66 |
| ▸ | LTA4H | P09960 | 7/20 | 0.61 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3866909 | 0.99 | ESR1 (0.67) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL13897796 | 0.99 | ESR1 (0.64) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL3872526 | 0.98 | ESR1 (0.66) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL6594554 | 0.95 | ESR1 (0.71) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL13897814 | 0.90 | ESR1 (0.74) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL13897645 | 0.90 | ESR1 (0.74) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL3861528 | 0.89 | ESR1 (0.76) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL13897535 | 0.89 | ESR1 (0.72) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL7110626 | 0.89 | ESR1 (0.59) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL13897593 | 0.88 | ESR1 (0.69) | ESR1ESR2LTA4HPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501441-B1 | Naphthyl compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501441-B1 | Naphthyl compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 2009-03-10 | — | — | US | disclosed |