Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899685 | 1.00 | KMT2A (0.50) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13899791 | 0.85 | KMT2A (0.51) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL13897542 | 0.85 | KMT2A (0.51) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL6087113 | 0.85 | MEN1 (0.62) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL6087108 | 0.85 | MEN1 (0.62) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13897706 | 0.78 | MEN1 (0.54) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13899605 | 0.78 | MEN1 (0.54) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13897921 | 0.77 | KMT2A (0.50) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13899699 | 0.77 | KMT2A (0.50) | KMT2AMEN1HSD17B10MAPTGAA | |
| SCHEMBL13897914 | 0.75 | KMT2A (0.53) | KMT2AMEN1HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511059-B2 | Thiazolidinones, their production and use as pharmaceutical agents | SCHERING AG (DE) | 2009-03-31 | — | — | US | disclosed |