⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20013272 | 1.00 | — | — | |
| SCHEMBL27650966 | 0.83 | — | — | |
| Phenol SCHEMBL28766018 | 0.80 | ESRRB (0.42) | — | |
| SCHEMBL23381280 | 0.80 | — | — | |
| SCHEMBL7354603 | 0.80 | — | — | |
| SCHEMBL3052834 | 0.80 | — | — | |
| SCHEMBL6692725 | 0.79 | — | — | |
| SCHEMBL20804159 | 0.79 | — | — | |
| SCHEMBL26857861 | 0.79 | — | — | |
| SCHEMBL25616126 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2015-12-24 | — | — | US | disclosed |
| US-9040531-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2015-05-26 | — | — | US | disclosed |
| EP-2379580-B1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARM INC (US) | 2013-10-23 | — | — | EP | disclosed |
| US-7511154-B2 | Preparation of N-protected-3-pyrrolidine-lactam substituted phosphonium salts | BASILEA PHARMACEUTICALS AG (CH) | 2009-03-31 | — | — | US | disclosed |
| US-20080009637-A1 | Preparation of N-protected-3-pyrrolidine-lactam substituted phosphonium salts | BASILEA PHARMACEUTICA AG | 2008-01-10 | — | — | US | disclosed |
| US-7262307-B2 | 1′-benzyl-3-bromo-[1,3′]bipyrrolidinyl-2-one | BASILEA PHARMACEUTICA AG (CH) | 2007-08-28 | — | — | US | disclosed |