Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PPARD | Q03181 | 12/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899473 | 0.88 | PPARA (0.54) | PPARAPPARDPPARGNR1H4 | |
| SCHEMBL13899282 | 0.86 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL13899244 | 0.83 | PPARA (0.50) | PPARAPPARDPPARGNR1H4 | |
| SCHEMBL13899466 | 0.81 | PPARA (0.62) | PPARAPPARDPPARG | |
| SCHEMBL13899511 | 0.81 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL13899214 | 0.73 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL13899432 | 0.72 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL13899451 | 0.72 | PPARA (0.46) | PPARAPPARDPPARGCTSVCTSB | |
| SCHEMBL13899419 | 0.72 | PPARD (0.63) | PPARAPPARDPPARG | |
| SCHEMBL13899240 | 0.71 | PPARA (0.45) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507832-B2 | Triazole PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507832-B2 | Triazole PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20070112045-A1 | Triazole ppar modulators | ELI LILLY AND COMPANY | 2007-05-17 | — | — | US | disclosed |
| US-20070112045-A1 | Triazole ppar modulators | ELI LILLY AND COMPANY | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112045-A1 | Triazole ppar modulators | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.