Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900836 | 1.00 | NOTUM (0.47) | NOTUMBAZ2BLMNAMAPTCYP1A2 | |
| SCHEMBL13900984 | 0.87 | CYP1A2 (0.44) | NOTUMCYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL13308642 | 0.80 | CYP1A2 (0.39) | NOTUMCYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL13900987 | 0.80 | CYP1A2 (0.39) | NOTUMCYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL13291999 | 0.74 | ESR2 (0.50) | LMNAMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18322651 | 0.74 | SRD5A2 (0.30) | — | |
| SCHEMBL770483 | 0.72 | CYP1A2 (0.43) | NOTUMCYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL13804058 | 0.72 | CYP1A2 (0.43) | NOTUMCYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL7379323 | 0.71 | — | — | |
| SCHEMBL14818732 | 0.70 | NOTUM (0.39) | NOTUMBAZ2BLMNAMAPTBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511144-B2 | Reverse hydroxamic acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |