Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.58 |
| ▸ | DPP4 | P27487 | 2/20 | 0.58 |
| ▸ | IDH1 | O75874 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932094 | 0.90 | PTPN1 (0.71) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL12040514 | 0.78 | PTPN1 (0.77) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7178845 | 0.75 | PTPN1 (0.78) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7178841 | 0.75 | PTPN1 (0.78) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7187194 | 0.74 | PTPN1 (0.76) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7177537 | 0.74 | PTPN1 (0.66) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7187188 | 0.74 | PTPN1 (0.76) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| SCHEMBL7177534 | 0.74 | PTPN1 (0.66) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| Licoagrochacone A SCHEMBL4906294 | 0.73 | PTPN1 (1.00) | PTPN1DPP4IDH1ABCB1UGT1A1 | |
| Licoagrochacone A SCHEMBL30383634 | 0.73 | PTPN1 (1.00) | PTPN1DPP4IDH1ABCB1UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009028839-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES COMPRISING LICOCHALCONE A | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-03-05 | — | — | WO | disclosed |