Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 17/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604955 | 0.88 | HTR2B (0.70) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604148 | 0.86 | HTR2B (0.70) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL13060028 | 0.86 | MEN1 (0.66) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1605161 | 0.85 | MEN1 (0.64) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604829 | 0.84 | MEN1 (0.61) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604029 | 0.84 | CNR1 (0.64) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604933 | 0.84 | HTR2B (0.65) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604942 | 0.84 | HTR2B (0.72) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604957 | 0.84 | HTR2B (0.60) | HTR2BMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1604665 | 0.82 | MEN1 (0.61) | HTR2BMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032885-A2 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS FOR TREATING FIBROSIS | EPIX DELAWARE, INC. (US) | 2009-03-12 | — | — | WO | disclosed |