Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561505 | 1.00 | CA1 (0.52) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL28316228 | 1.00 | CA1 (0.52) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL12561509 | 0.88 | GLB1 (0.40) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL12561507 | 0.88 | GLB1 (0.40) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL24477566 | 0.83 | CA1 (0.52) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL7225817 | 0.83 | CA1 (0.52) | CA1CA2CA4GBA1KCNH2 | |
| SCHEMBL26734150 | 0.83 | — | — | |
| SCHEMBL26734347 | 0.83 | — | — | |
| SCHEMBL12536900 | 0.83 | — | — | |
| SCHEMBL9901175 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033084-A1 | PYRAZOLO-PYRIDINES AS TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2009-03-12 | — | — | WO | disclosed |