Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906466 | 0.74 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL13906474 | 0.68 | MAPT (0.38) | KDM4EALDH1A1 | |
| SCHEMBL829831 | 0.66 | CDK5 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL832080 | 0.64 | CDK5 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL12665725 | 0.64 | CDK5 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL12388707 | 0.61 | AURKA (0.35) | KDM4EALDH1A1 | |
| SCHEMBL12622957 | 0.61 | CDK4 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL13395672 | 0.61 | CDK4 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL12388717 | 0.60 | PARP1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL16751651 | 0.58 | AURKA (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032123-A2 | TETRACYCLIC INDOLE DERIVATIVES AND THEIR USE FOR TREATING OR PREVENTING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2009-03-12 | — | — | WO | disclosed |