⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12785153 | 0.87 | — | — | |
| SCHEMBL3196846 | 0.79 | — | — | |
| SCHEMBL12959772 | 0.70 | — | — | |
| SCHEMBL6600564 | 0.69 | — | — | |
| SCHEMBL239887 | 0.69 | — | — | |
| SCHEMBL11074596 | 0.69 | — | — | |
| SCHEMBL3440747 | 0.69 | — | — | |
| SCHEMBL8984099 | 0.67 | TTR (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL20838553 | 0.65 | — | — | |
| SCHEMBL12656248 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373932-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-23 | — | — | US | claimed |
| US-20210130300-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2021-05-06 | — | — | US | claimed |
| EP-3744713-A1 | DIYHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF | Japan Tobacco Inc. (JP) | 2020-12-02 | — | — | EP | claimed |
| EP-3231793-B1 | DIHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF | JAPAN TOBACCO INC (JP) | 2020-03-11 | — | — | EP | claimed |
| EP-3231793-A1 | DIHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF | JAPAN TOBACCO INC. (JP) | 2017-10-18 | — | — | EP | claimed |
| US-20160194290-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2016-07-07 | — | — | US | claimed |
| US-20070265228-A1 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-15 | — | — | US | claimed |
| US-20060211680-A1 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-21 | — | — | US | claimed |
| EP-1671961-A1 | CINNAMOYL COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-21 | — | — | EP | claimed |
| EP-1671948-A1 | CINNAMOYL COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-21 | — | — | EP | claimed |
| US-3947504-A | BY-PRODUCT IN PRODUCTION OF ISOPRENE | KURARAY CO., LTD. (JA) | 1976-03-30 | — | — | US | claimed |
| JP-58201775-A | — | — | None | — | — | JP | disclosed |
| JP-7126261-A | — | — | None | — | — | JP | disclosed |
| JP-5170770-A | — | — | None | — | — | JP | disclosed |
| JP-8127577-A | — | — | None | — | — | JP | disclosed |
| EP-0259814-B1 | PROCESS FOR THE PRODUCTION OF 4-FORMYL TETRAHYDROPYRANES, AND 4-FORMYL TETRAHYDROPYRANES | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |
| US-4824973-A | Preparation of 4-formyltetrahydropyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |
| EP-0259814-A1 | Process for the production of 4-formyl tetrahydropyranes, and 4-formyl tetrahydropyranes | BASF Aktiengesellschaft (DE) | 1988-03-16 | — | — | EP | disclosed |
| JP-S58201775-A | PREPARATION OF 3,4-DIHYDRO-2H-BENZOPYRAN DERIVATIVE | KURARAY CO LTD | 1983-11-24 | — | — | JP | disclosed |
| US-3947504-A | BY-PRODUCT IN PRODUCTION OF ISOPRENE | KURARAY CO., LTD. (JA) | 1976-03-30 | — | — | US | disclosed |