Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.76 |
| ▸ | BCL2 | P10415 | 14/20 | 0.76 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.74 |
| ▸ | ALB | P02768 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954119 | 1.00 | BCL2L1 (0.76) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL3957485 | 0.95 | BCL2L1 (0.77) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL13906742 | 0.95 | BCL2L1 (0.77) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL3958388 | 0.93 | BCL2L1 (0.79) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL13906739 | 0.93 | BCL2L1 (0.79) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL19425592 | 0.92 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL13906748 | 0.89 | BCL2L1 (0.79) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL3956718 | 0.89 | BCL2L1 (0.79) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL19425645 | 0.86 | BCL2L1 (0.63) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL13906747 | 0.85 | BCL2L1 (0.74) | BCL2L1BCL2BCL2L2ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036035-A1 | BCL-2 INHIBITORS | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |